>>110900
Means she looks swollen, as when you have an allergic reaction. During the anaphylactic process, an allergen can stimulate a couple types of immune or nerve cells to release granules of high concentrations of histamine, which is continuously synthesized in these cells from histidine by L-histidine carboxylase. In particular, from mast cells and basophils. The released histidine has pleiotropic effects, but is a particularly powerful vasodilation, hypotension-inducing and increased vascular permeability signal, mediated through its interaction with H1 G-protein coupled receptors on blood vessel epithelia.
Epinephrine is a hormone with itself pleiotropic effects, agonizing a variety of receptors throughout the body. But in our case, in consideration of the freaking joke, it interacts with alpha 1 andrenergic receptors, whose activation induces vasoconstriction and therefore increased resistance in the vasculature, and a rebound of blood pressure, counteracting some of histamine's potentially life-threatening effects. Epinephrine is most commonly prescribed in the form of a pen autoinjector, which you can stick into your leg for immediate treatment of a severe allergic reaction.
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